Chemical reagents and indicators play an important role in the preparation and analysis of chemicals, pharmaceuticals, industrial, biological, medical and healthcare products. The term quality in the world of chemicals refers to the purity and also impurities of that material, and specifies that for what applications it can be used.

Therefore, in order to facilitate the use of chemicals in various applications, they have been classified into various grades of chemicals with specific characteristics and various qualities. Higher grade chemicals can also be used for lower sensitivity applications.

The table below summarizes the compatibility of different grades in order to facilitate the selection of our products. Each grade given in the left column can be used in the applications listed in the right column. For example, dried solvents can also be used as ACS, USP, Laboratory, Extra pure and Synthesis, but cannot necessarily be used for chromatography or UV Spectrophotometry studies.

Grade Covered grades
Gradient chromatography Isocratic chromatography, UV Spectrophotometry, ACS, USP, Laboratory, Extra Pure, For Synthesis
Isocratic chromatography UV Spectrophotometry, ACS, USP, Laboratory, Extra Pure, For Synthesis
Gas chromatography Isocratic chromatography, UV Spectrophotometry, ACS, USP, Laboratory, Extra Pure, For Synthesis
Dried ACS, USP, Laboratory, Extra Pure, For Synthesis
UV Spectrophotometry ACS, USP, Laboratory, Extra Pure, For Synthesis
ACS USP, Laboratory, Extra Pure, For Synthesis
USP Extra Pure, For Synthesis
Laboratory Extra Pure, For Synthesis
Extra Pure For Synthesis
Histology N/A
Cleaning and disinfecting solution N/A
Titrant N/A
pH buffer N/A
Electrical Conductivity N/A
Dried

Most of the chemical reactions that take place in a non aqueous environment can be very sensitive to minute amounts of water. Therefore, for analysis or organic synthesis in a dry environment, solvents with a very low amounts of water should be used. Dry solvents are also used to determine the water content of chemicals by the Karl Fischer method and in modern inorganic and organic research methods. DRM provides dry grade solvents with very minute amount of water within the acceptable range specified in pharmacopeia of different countries.

In such reactions that are sensitive to very low amounts of water, it is recommended to use solvents of dried grade.

Gradient chromatography

Solvents suitable for gradient liquid chromatography, in addition to very high transparency in the visible-ultraviolet region, should have very small amounts of water, acid, alkalinity and solid residue after evaporation. To achieve such precise specifications, we manufacture gradient liquid chromatography solvents using high-quality raw materials and advanced distillation equipment. Passing through a 0.2 micron filter is an essential process in the production of chromatographic solvents, which is performed just before the packaging process. These solvents are suitable for a variety of liquid chromatography techniques.

Isocratic chromatography

Solvents of this category have gradient grade purity. Since the sensitivity in the isocratic liquid chromatography method is less than that of the gradient type, we offer special isocratic chromatography solvents that bring high resolution separation along with lower operating costs.

spectroscopic grade

In spectrophotometric studies, obtaining reliable results is highly dependent on the use of ultrapure solvents in the sample preparation stage. Suitable solvents of this category should not only have high transparency in the visible and ultraviolet spectrum, but the presence of impurities such as water, alkali and acid should also be controlled at an extremely low level. Also, the amount of non-volatile residue after boiling should be very low. DRM has processed the solvents of this grade using high quality raw materials, so that the specifications of the American Chemical Society for spectrophotometric studies are met.

gas chromatography grade

Solvents of this grade are used in gas chromatography studies. This feature is not only due to their high purity, but also due to the presence of small amounts of water, acid and alkali, as well as the absence of additional peaks in gas chromatography analyses. Our gas chromatography grade solvents are purified and supplied with precise specifications to meet the different applications such as sample preparation and dissolution in gas chromatography studies.

ACS grade

The American Chemical Society has determined technical specifications and purity for approximately 500 reactive chemicals and more than 500 standard reference materials, so that they are accepted by researchers and industrialists around the world. DRM offers various types of chemicals, reagents and standard solutions in accordance with ACS specifications to ensure reliable results even for extremely sensitive tests.

USP grade

The United States Pharmacopeia has defined specifications for chemicals used as raw materials in the pharmaceutical industry. Materials with USP grade have the necessary standards for use in the pharmaceutical and food industries and are used in world leading laboratories. DRM, due to having GMP certificate, produces a wide range of chemicals with USP grade, which have been quality approved in a well-equipped laboratory according to USP test protocols.

BP grade

BP grade products are in accordance with the standards set by the UK National Pharmacopoeia in terms of purity and absence of impurities. This pharmacopoeia is a set of quality standards for the production of medicinal substances that is published annually in the UK and is used by individuals and organizations involved in the testing, research, development and production of medicinal substances and compounds DRM, by obeying the GMP rules and regulations has recently started producing chemicals with BP grade, all of which have been quality approved based on BP standards and tests.

EP grade

EP grade is defined as pharmaceutical grade according to the European Pharmacopoeia. This pharmacopoeia contains a series of official standards for pharmaceutical compounds available in Europe, which are used in the production stages of bulk pharmaceuticals, chemical and biological analysis methods, reagents, and auxiliary substances of drugs. The standards of this grade are seriously applied in the preparation of raw materials and active pharmaceutical ingredients. DRM has recently started producing chemicals with EP grade.

laboratory grade

Laboratory grade materials are often used in laboratories and research and educational institutions. Although the purity of these materials is high, the exact amount of their impurity is not known. As a result, this category of materials is not recommended for pharmaceutical, food and medical applications. We manufacture a wide range of laboratory grade chemicals including acids, bases, salts and solvents to cover the sensitive needs of various laboratories. The specifications of laboratory chemicals are set in such a way that they can be used for different applications.

View Extra pure grade

Extra pure grade is related to products that are suitable for qualitative and semi-quantitative use. This category of chemicals is suitable for general laboratory work and in most cases they have pharmacopoeia standards such as BP and USP. In order to cover general applications in laboratories where low sensitivity and low operating costs are important, we offer a wide range of chemicals including acids, salts and solvents with this grade.

histology grade

Chemicals that are mostly used in clinical and pathobiology laboratories are produced under the title of histology grade. These products are tested according to international standards in order to best cover the needs of customers in medical diagnostic laboratories. In DRM, all the production steps of materials with this grade are carried out in accordance with ISO 13485 guidelines.

cleaning solutions and disinfectants

برای تمیز کردن و یا ضد عفونی نمودن سطوح، ظروف و دست‌ها، ما محلول‌های شیمیایی متعددی را تولید می‌کنیم که به صورت ویژه برای افزایش کارایی گندزدایی طراحی شده‌اند.

** As a brief guide, you can find your application in the “Typical application” column and then select the appropriate chemical grade from the left column. The “Norms” column indicates which globally accepted references each grade offered by DRM, if you do not find the table helpful, you can contact the experts of DRM to guide you sincerely.

Grade Typical application Norms
Gradient chromatography Gradient liquid chromatography, Ultra-sensitive analytical applications ACS
Isocratic chromatography Isocratic liquid chromatography,  Ultra-sensitive analytical applications
Gas chromatography GC-FID, Head space
Dried Karl-Fischer titration, sensitive organic reactions
UV Spectrophotometry Sample preparation in UV spectrophotometry ACS
ACS Ultra-sensitive and sensitive analytical applications, preparation of reagents ACS
USP Pharmaceutical production process USP
Laboratory Sensitive analytical applications,  preparation of reagents
Extra Pure Routine applications, classical analysis, cleaning and rinsing
For Synthesis Chemical synthesis,  Routine applications,  cleaning and rinsing
Histology Clinical laboratories
Cleaning and disinfecting solution Cleaning glassware, disinfection of surfaces & laboratory equipment
Titrant Sophisticated titration ACS, USP
pH buffer Calibration of pH meter ACS, USP, DIN
Electrical Conductivity Calibration of EC meter USP
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